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Since Myriad owns the patent on breast cancer genes, it was the only company that could perform tests for potential abnormalities.

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It says 1 million patients have benefited from its "BRAC Analysis" technology, and that about 250,000 such tests are performed yearly.

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An initial test catches most problems, but the company also offers a second called BART to detect the rest,

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a diagnostic that can cost several thousand dollars.Jolie had Myriad's breast cancer test.

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Plaintiffs and testing Among those challenging the Myriad patents were sisters Eileen Kelly and Kathleen Maxian.

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Kelly was diagnosed with breast cancer at age 40. The initial BRCA test proved negative, meaning her family members were not likely at risk.

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But Maxian later developed ovarian cancer. The second BART testing proved positive, meaning the siblings carried the cancer-causing mutation all along.

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Money was not an issue for them, but Kelly and Maxian,

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